Joker Infection
Two years ago, I uncovered Joker's plan to unleash a genetically-enhanced army on Gotham. The drug he used to modify his henchmen was called Titan. Before I could stop him, Joker ingested a massive dose of the Titan formula and mutated into a gigantic abomination. I managed to defeat him, but his overdose had devastating side-effects. Joker was dying and he needed a cure. To ensure my cooperation, he infected my blood with his own, leaving me no choice but to help him. But that wasn't all. He contaminated Gotham's blood banks too. The result: the patients currently quarantined here. Joker's blood behaves likes a prion infection, attacking the brain and transforming these people... into him. Unless we find a way to reverse the process, no-one will be able to stop what he's unleashed.
— Batman on the Joker Infection.” The Joker Infection was a unique condition created by the Joker's mutated blood that slowly turned those infected into direct copies of him.
https://arkhamcity.fandom.com/wiki/Joker_Infection
TITAN is a chemical compound created by Dr. Penelope Young and used by the Joker via research on the chemical compound, Venom, and Poison Ivy's plants. Like Venom, TITAN can turn any user into a Bane-like monster, also known as a Titan. However, only a small amount is needed to trigger a long lasting transformation.
Before Arkham Asylum incident
TITAN was originally conceived by Dr. Penelope Young as a way for weaker patients to survive more strenuous treatments. Additionally, it's believed that Scarecrow had aided in its creation. However, Young's source of funds Jack White, who was in reality, the Joker, intended to use the compound to create an "army of a thousand Banes".
Bane was secretly brought to Arkham Asylum from Blackgate Prison (arranged by the Joker). Joker's plan was to have Dr. Young study him and the effects of Venom on the human body, so that she could develop TITAN, a more powerful variant of Venom. When discussing the TITAN Project in public, Bane's involvement was kept secret, and he was referred to only as "Patient X". Officially, Bane was listed as an escapee from Blackgate to cover-up his transfer (Batman and the GCPD were led to believe that he had escaped from Blackgate). During that time, Bane was forced against his will to be a human guinea pig for the TITAN Project.
One of their first test subjects was Katie Burke, the daughter of millionaire, Edward Burke. She was diagnosed with a deadly disease, and her father started looking for a cure. He found a doctor that offered her help, Dr. Harleen Quinzel. She introduced Edward to a friend of hers, Jack White (Joker). As Joker persuaded Edward to build an amusement park on an oil rig, Harley pretended to do tests, and claimed that the only way that Katie could be cured was through the use of TITAN, the experimental drug. Ready to try anything to cure his daughter, Edward agreed with the decision. As expected, Katie died painfully, which drove her father to commit suicide, and allowed Joker to take control of the amusement park.
Arkham Asylum Incident
While Dr. Young discovered the true identity of her benefactor and attempted to kill the project, research had already progressed into the production phase. Intent on obtaining the formula, Joker formulated the Arkham Asylum Incident partially to obtain the TITAN and create his "monster army". Joker succeeded in using the formula on six of his henchmen and two Arkham Guards, which transformed them into Bane-like creatures as well as on Poison Ivy, which enhanced her powers and nearly destroyed Arkham Island with killer plants and finally himself. Joker also used TITAN on Bane against his will to have him fight against Batman and to test out the TITAN's effects.
It was revealed by Poison Ivy that there was a counter-compound/antidote to TITAN, which originated from unique plant spores that were found in Killer Croc's Lair. Batman was able to obtain some spores and liquefied them to make an antidote. Unfortunately, Ivy's plants destroyed the Bat-Computer that was mass-producing the antidote. Luckily enough, the TITAN eventually wore off on its own, and returned the affected individuals to normal, including the Joker, who used it on himself as a last resort to kill Batman. Though the original TITAN compound and TITAN formula was destroyed, one crate that contained mass produced Titan was left floating in the water.
After Arkham Asylum Incident
Following the Incident at Arkham Asylum, it was revealed that the TITAN mixture made its way into the Gotham City underground. Crates of the compound floated into the docks and Two-Face bought it hoping for quick cash. Little did Two-Face realize the mistake of having Brother-Sister team Terry and Tracy Trask take the TITAN into his cellar. Upon discovering what it was, the siblings started using it and turned the cellar into a personal training ground.
After slaughtering Two-Face's gang and putting the man himself into several casts, T&T started making plans to take over the city under the employment of Hugo Strange. Unfortunately for them, Batman arrived in time to save the city, but before he could trace T&T back to Hugo Strange, they committed suicide via high explosives that were planted inside their bodies, which killed hundreds and blew up Gotham City Hall.
The purpose of the entire incident was later revealed to act as a trigger to give Mayor Quincy Sharp the excuse that he needed to create Arkham City.
Additionally, the Joker was still suffering from the side-effects of his TITAN overdose, which mixed with the toxins in his blood and mutated into a extremely toxic poison with an estimated six months to live. Joker was planning to use the TITAN again after he had a doctor, which he promptly sent into the incinerator, isolate the TITAN from his blood. In addition, the Joker had some of the TITAN formula that was isolated from his blood injected into one of his henchman, and then sent him after Bane.
After the henchman had managed to place Bane at his mercy, he started to suffer from cardiac arrest, which resulted in Bane having to mercy kill him. Due to that experience, Bane also vowed to destroy the source of all TITAN by any means necessary. This led Bane to Penguin's latest gang initiation where he demanded that Penguin hand over all of his TITAN immediately.
While Bane was able to defeat Penguin's TITAN Henchman, he was forced to retreat by Solomon Grundy.
Arkham City Incident
After his encounter with the TITAN-infused thug, Bane launched a crusade against the existence of the TITAN drug, and devoted himself to the eradication of the compound. However, Bane soon decided that it was best to use the TITAN to enhance his own strength instead. Realizing that he couldn't do it alone, Bane signaled Batman with a flare and lured him into the abandoned Krank Co. Toy Factory at Amusement Mile in the flooded section of Arkham City. There, Bane alerted Batman to the twelve TITAN containers remaining within Arkham City.
Bane gave Batman six containers in southern Arkham City, while he would take the six in the northern area.
The locations of the six that Batman had to destroy were:
- Industrial District guarded by three of the Joker's henchmen.
- Inside the Steel Mill.
- At the base of Wonder Tower
- In the Subway, by a Solomon Grundy poster that is also a riddle.
- Bowery, beneath street level.
- Museum War Room
Even though the containers' locations were marked on the map, Batman could see their specific location from a distance using Detective Mode. In order to destroy them, Batman sprayed the container with Explosive Gel. Once Batman had destroyed all six, he returned to Krank co. Toys. Depending on whether Batman returned before or after Protocol 10, either TYGER personnel or Joker's men would burst in and demand the containers be handed over. After they had been defeated, Batman soon learns that Bane hadn't destroyed his six and wanted the Titan all to himself him then tried kill Batman, the Dark Knight however quickly trapped him in a room using a Batarang. Bane's containers, that had been grouped together inside Krank Toys were then blown up by Batman too.
Meanwhile, the Joker; dying from his previous exposure to the TITAN compound during the Arkham Asylum Incident, used his infected blood to poison stores of medical blood across Gotham, infected Batman himself, and used this as a bargaining chip to force Batman to find a cure for the poison before it killed them both as well as the infected Gotham citizens. Batman contacted Mister Freeze for research into a cure, and Freeze revealed that he had made an unstable formula that could theoretically work.
Noting that all the formula needed was a specific enzyme that could be found in the blood of Ra's al Ghul (due to his constant usage of the Lazarus Pit), Batman managed to locate the League of Assassins stronghold underneath Arkham City in Wonder City, and obtained a sample of Ra's blood. Returning the sample to Freeze, Harley Quinn managed to steal the developed cure as Freeze was attempting to use it as a bargaining chip to force Batman to find his wife, Nora.
The cure was in turn stolen from Harley by Talia al Ghul which prompted Joker to kill her for it, and the cure then wound up in the hands of Clayface. When Batman defeated Clayface and took the cure. Batman managed to cure himself just before Joker, who believed that Batman would never give him the cure, stabbed him in the arm in an attempt to get at it. This prompted Batman to drop the vial, where it smashed on the floor.
Unable to cure himself, and laughing at the irony that Batman would have given him the cure had he not attempted to steal it, the Joker succumbed to his TITAN poisoning, and died. Batman apparently missed some of the TITAN, as Harley Quinn used it on one of her thugs two weeks after Batman and Bane's alliance.
Between Arkham City and Arkham Knight
Though cured of the fatal condition the TITAN-infected blood had caused, Batman could sense that something was still up the now-deceased Joker's sleeve. He soon found four transfusion bags of Joker's blood were unaccounted for, which resulted in four people being infected with it. Christina Bell, Johnny Charisma, Albert King, and Henry Adams were detained by Batman and studied. As a result of the infected blood gestating in Bell, King, and Charisma for too long, they were beginning to look and act like Joker, although with only a specific aspect of the late Clown Prince of Crime's personality; Bell had Joker's obsession with Batman, Charisma had Joker's egomania and flamboyancy, and King had Joker's sadism. Only Henry seemed immune to this. Remembering that Joker's blood was still in his own veins, Batman kept a fifth cell for himself ready, just in case he ever succumbed to the influence of the deranged clown's blood.
Batman tested Henry constantly to see what was allowing him to resist Joker's influence; however, he didn't keep his promise that detaining him would only last a few days. By the time Batman brought Gordon in on this experiment, Henry was begging for help in being released; however, Gordon sided with Batman.
Arkham Knight Incident
In truth, Henry was infected, but was able to hide the effects. He made contact with Harley Quinn prior to Batman incarcerating him, and plotted with her to free the new Jokers, with the hidden intention of killing them to purify the gene pool. Scarecrow's Fear Toxin only accelerated the process in Batman, which caused him to see the Joker talking to him whenever he was facing a trying situation. Dropping the charade, Henry killed Bell, Charisma and King; he held Quinn hostage to force Batman to cooperate. The consciousness of Joker was impressed with this old man, momentarily becoming undecided on either to root for him or Bats. However, when Henry threatened to kill Batman next, Joker sided with his old foe; he then urged Batman to kill Henry, causing Batman's eyes to glow green. Seeing this, Henry judged Batman to be the "best" Joker, and committed suicide as a result.
Batman later was injected with 10 vials of Scarecrow's improved Fear Toxin, which caused the Joker to surface. This began a mental battle between Batman and the Joker, and showing him the only fear that the Clown Prince of Crime had - being forgotten, with only Harley remembering him at all. Confronting the Joker in a version of Arkham Asylum, Batman managed to finally instill the fear in Joker that he never could before, and locked him away in a dark corner of his mind, permanently.
Effects
- Physical Enhancement: TITAN was much more potent than Venom, and required only a small amount for a Bane-like reaction, resulting in developing inhuman amounts of muscle mass and bone strength.
- Insanity Inducement: The treatment had a price, as the sudden release of endorphin and adrenaline, along with the extreme pain of the transformation, resulted in the recipient going into a crazed, psychotic state. Only Bane (due to his extreme intelligence, will, and his previous usage of Venom and the TN-1), Poison Ivy (due to her natural immunity to toxins), and the Joker (because of his high intelligence and his psychopathy) retained their personalities (at least, partially) and some of their intelligence.
- Joker's Transformation: In the case of the Joker, he retained his normal personality after injection, as he was already insane, and actually enjoyed the painful transformation, which in his case, caused his exposed spinal column to resemble a set of dorsal fins. Batman, having taken a TITAN-filled dart meant for the captive Commissioner Gordon, chose to resist the change and used the antidote on himself, much to the Joker's chagrin. It was possible that the drug had reduced even the Joker's intelligence, for while the fight was a ferocious one, Batman had no trouble in finding a strategy to bring him down.
- Health Degeneration: Joker's overall health, he did not look well when he was shown in withdrawal during the game's closing scenes, nor did his formerly enhanced henchmen. The subjects underwent not only a size change, but also grotesque facial and muscular disfigurement, which even caused their spinal columns to become exposed. Earlier versions of TITAN often killed the test subjects due to the massive shock to the body that caused it to fail and die from the compound soon after receiving it.
https://arkhamcity.fandom.com/wiki/Titan
Protocol 10
Protocol 10 was devised by Hugo Strange and Ra's al Ghul to wipe out the criminal element in Arkham City, along with anyone else that could pose a threat to them by revealing the secrets about the prison - Political Prisoners. Presented to the Gotham City Council as a last resort if the inmates gained access to weapons and were planning a mass breakout, that procedure would grant the TYGER Guards full permission to exterminate the inmates with missile strikes via helicopter.As extra insurance that major threats like the super criminals were eliminated by Protocol 10, Strange had the Observation Deck of Wonder Tower modified to hold several missile launchers. These missiles would be more powerful than the ones launched by the helicopters and were capable of taking out a large portion of a building.https://arkhamcity.fandom.com/wiki/Protocol_10
Protocol 11
Protocol 11 was devised by Professor Hugo Strange as a self-destruct mechanism for Wonder Tower to be used in the event that it was compromised by his enemies, especially Batman.
The passcode to this protocol was Batman's last name of "Wayne".
Protocol 11 was devised as a self-destruct order should Batman decide to venture to Wonder Tower.
As Strange lay dying at the hands of Ra's al Ghul with Batman beside him, he activated the protocol in the hopes of killing both Batman and Ra's. Batman survived the explosion and so did Ra's, but the latter impaled himself with his sword in an attempt to kill Batman and then was impaled by the Arkham City front gates.
Arkham Knight Incident
Protocol 11 was inadvertently the cause of The Shadow War. Ra's injuries from the explosion and his impalement led to him being resurrected with an impure Lazarus Pit beneath Elliot Memorial Hospital. This left him in a zombified state and many members of the League of Assassins wanted to put him out of his misery. Others opposed doing so and lead to a civil war among the League.https://arkhamcity.fandom.com/wiki/Protocol_11
The Shadow War was a civil war that began after Protocol 10 between rebels and loyalists of the League of Assassins.
Prelude
While Ra's al Ghul was gloating that Protocol 10 would be a success, Hugo Strange, his disgraced minion, activated Protocol 11. Protocol 11 caused Wonder Tower to explode, although Batman and Ra's were able to barely escape. As Batman was about to arrest the Head of the Demon, he took his sword and committed suicide mid-air.
After the death of Ra's al Ghul, a group of loyalists took his body and sword. They attempted to resurrect their master with an impure Lazarus source. This only brought him back as a barely conscious zombie.
Insurrection
Ra's daughter, Nyssa Raatko, decided that her father should be put out of his misery. The Loyalists refused, asserting that their master would return to eventually full strength. For Nyssa, eventually was not good enough. So, she created a rebel faction in order to prevent the resurrection of her father and to ensure that no more innocents would be hurt in the crusade for justice.
Shadow War
On Halloween Night, Alfred alerted Batman that a GCPD officer just witnessed two "crazy ass ninjas" fighting on Miagani Island. Batman investigated and found two dead ninjas wearing different outfits and a sword with blood on it. He followed the blood trail to Elliot Memorial Hospital. He noted that neither Ra's nor the League had been seen since the body of Ra's disappeared in Arkham City. At Elliot Memorial, Batman saw new members being trained by a member of the League. He learned that there were two factions of the League: the Loyalists and the Rebels. Batman learned that the Loyalists had returned to Gotham, in the hopes of fully restoring Ra's. The Rebels wanted to ensure that the Demon's Head was never brought back. Batman was tasked by the Loyalists with finding a pure source of Lazarus chemicals to heal Ra's or else the war between the assassins would destroy the city.
Batman used the Batmobile to track the source of Lazarus under Panessa Studios. After finding the last pool of Lazarus in Gotham (and possibly on Earth), he was attacked by the Rebels. After defeating them, he took a sample of Lazarus and attempted to destroy the rest with Explosive Gel. He was then stopped by the leader of the Rebels, Nyssa Raatko. Nyssa then asked Batman to destroy her father's life support and let her take over, before detonating the Explosive Gel herself.
When Batman returned to Elliot Memorial, Alfred tried to convince him to let the Demon's Head die. Batman contemplated his options as he headed for Ra's life support. If Ra's were to die, the assassins would leave Gotham. If he did disconnect Ra's from his machine, he would be breaking his no kill rule.
Outcome
If Batman decides to give Ra's the Lazarus cure, he injects him with the pure Lazarus. Immediately after, the Rebels attack intent on killing Batman for betraying them. After Batman defeats all of the Rebels, he is attacked by Nyssa asking why he would help a man as evil as Ra's. Ra's returns to strength and accuses his daughter of being a traitor. He then slashes her in the stomach, leaving her to bleed out. Batman then attacks Ra's, but Ra's is able to steal one of Batman's Smoke Bombs and escapes. Batman consoles Nyssa in her final moments. Alfred then tells Batman that he has stopped a terrible war and he would not have to worry about the League for a while because it will take time for Ra's to heal and the Rebels have scattered. At GCPD, some of the Rebels are placed in holding cells and call the Dark Knight "traitor". Their weapons and uniforms are then placed in the Evidence Room.
If Batman decides to destroy Ra's life support, he uses two Batarangs to destroy the machine, which causes the Loyalists to attack intent on killing Batman for his betrayal. After Batman defeats the Loyalists, Ra's tries to crawl away. He is then confronted by Nyssa, who is disgusted by what he has become. She attempts to deliver her father a killing blow, but she is stopped by Batman. She tells the Dark Knight that her father will die in a few days anyway. She fulfills her promise by taking control of the League of Assassins and leaving Gotham forever. Batman takes Ra's to the GCPD. After locking the former Master of Assassins away, Ra's thanks the "Detective" (Batman) for doing the right thing. After six centuries, the Demon's Head is ready to pass away peacefully. At GCPD, some of the Loyalists' weapons and uniforms are then placed in the Evidence Room.
https://arkhamcity.fandom.com/wiki/The_Shadow_War
Lazarus Pit
The Lazarus Pit was a natural phenomenon of mythical vats of arcane chemicals which had blended together to create a revolutionary regenerative serum that was used most commonly used by Ra's al Ghul to ensure his longevity and eternal youth as well heal all of his wounds instantaneously.
The substance that filled each pit was a chemical blend of unknown composition, that seemingly originated from somewhere within the Earth's crust. It bubbled to the surface only at certain key points around the globe, typically at the junction of key lines.
Although capable of healing any injury, restoring youth and even restoring life, the pits had the temporary side-effect of casting the dweller into temporary aggressive insanity. This effect did wear off after a short time.
https://arkhamcity.fandom.com/wiki/Lazarus_Pit
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