Dr. Anthony Fauci is calling it: mRNA COVID-19 vaccines can provide people with better protection against new viral variants than a prior coronavirus infection alone can.
During
a White House COVID-19 briefing on Tuesday, Fauci pointed to several
new studies, which, when taken together, suggest that the mRNA vaccines
from Pfizer and Moderna provide great immune protection against newly
circulating viral variants.
According to the data, the vaccines bump up any natural protection people may have had from prior infection substantially.
"Vaccines,
actually, at least with regard to SARS-CoV-2 [the coronavirus] can do
better than nature," Fauci, America's leading infectious disease expert,
said. "Vaccination in people previously infected significantly boosts
the immune response."
Two of the studies
that Fauci referenced during the briefing have been peer-reviewed,
meaning other independent scientists have given them a thumbs up, while two others are still awaiting peer approval. But they all tell a very similar story.
Four studies all show superior protection against variants from vaccines
One study
found that people who'd had two doses of an mRNA coronavirus vaccine
(either Pfizer's or Moderna's) had antibody titer levels "up to 10
times" that of a natural infection, Fauci said, suggesting those vaccines give people's bodies more fighting power against viral variants than a prior illness can.
"You had interesting increased protection against the variants of concern," Fauci said.
Another small study showed that previously infected people who got vaccinated were exceptionally well protected against three of the five major variants of concern:
the P1 variant, first identified in Brazil, the B.1.1.7 variant from
the UK which is now dominant in the US, and the B.1.351 variant, first
found in South Africa.
But that's not all. In another study that Fauci mentioned,
people who'd been previously infected with COVID also displayed better
T-cell immunity after a single dose of Pfizer's mRNA vaccine. (T cells can help make infections milder, if people do ever get reinfected.)
"Now,
remember these are only laboratory data, have not been proven in the
clinic," Fauci said, pointing out that the new studies are based on
blood tests, so it's hard to know exactly how everything would play out
with real-world infections and variants. "But they are really very
interesting, and things that we need to follow up on," he added.
The final study Fauci cited
suggested that people who have recovered from a prior COVID-19
infection who then get vaccinated may receive great broadband
protection, not just against concerning viral variants, but also against
other coronaviruses, like SARS, from their COVID-19 vaccination. That's
a virus-fighting power that people who've been infected but not
vaccinated don't get.
"Vaccines are highly efficacious," Fauci
concluded. "They are better than the traditional response you get from
natural infection."
https://www.businessinsider.com/fauci-why-covid-vaccines-work-better-than-natural-infection-alone-2021-5
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