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The Pitié-Salpêtrière Hospital (Groupe hospitalier Pitié-Salpêtrière) is a celebrated teaching hospital in the 13th arrondissement of Paris.^[1] Part of the Assistance publique - Hôpitaux de Paris, it is one of Europe's largest hospitals.^[2]

The Salpêtrière was originally a gunpowder factory ("salpêtre" being a constituent of gunpowder), but was converted to a dumping ground for the poor of Paris. It served as a prison for prostitutes, and a holding place for the mentally disabled, criminally insane, epileptics, and the poor; it was also notable for its population of rats.
In 1656, Louis XIV charged the architect Libéral Bruant to build a hospital on the location of the factory, founding the Hospice de la Salpêtrière. The building was expanded in 1684.
By the eve of the Revolution, it had become the world's largest hospital, with a capacity of 10,000 patients plus 300 prisoners, largely prostitutes swept from the streets of Paris. From La Salpêtrière they were paired with convicts and forcibly expatriated to New France.

During the September massacres of 1792, the Salpêtrière was stormed on the night of 3/4 September by a mob from the impoverished working-class district of the Faubourg Saint-Marcel, with the avowed intention of releasing the detained street-girls; 134 of the prostitutes were released; twenty-five madwomen were less fortunate and were dragged, some still in their chains, into the streets and murdered.^[3] Madame Roland, a Girondin supporter of the Revolution in its first liberalising stages, recorded in her Memoirs that the Revolution "has been stained by villains and become hideous".^[4]

In the first half of the 19th century, the first humanitarian reforms in the treatment of the mentally ill were initiated here by Philippe Pinel, friend of the Encyclopédistes; his sculptural monument stands before the main entrance in Place Marie-Curie, Boulevard de L'Hôpital. Later, when Jean-Martin Charcot took over the department, the Salpêtrière became known as a psychiatric centre. Charcot is often credited as the founder of modern neurology, although he had absorbed much from his teacher Duchenne de Boulogne. Charcot's teaching activities on the Salpêtrière's wards helped to elucidate the natural history and pathophysiology of many diseases including neurosyphilis, epilepsy, and stroke. Students came from all over Europe to listen to Charcot's lectures. Among them - in 1885 - was the young Sigmund Freud.
The Hôpital de la Pitié, founded about 1612, was moved next to the Salpêtrière in 1911 and fused with it in 1964 to form the Groupe Hospitalier Pitié-Salpêtrière. The Pitié-Salpêtrière is now a general teaching hospital with departments focusing on most major medical specialities.

Numerous celebrities have been treated at the Salpêtrière, including Michael Schumacher,^[5] Ronaldo,^[5] Prince Rainier of Monaco,^[6] Alain Delon, Gérard Depardieu, and Valérie Trierweiler.^[7] Former president Jacques Chirac had a pacemaker fitted at the Salpêtrière in 2008.^[8] Celebrities have also died at the Pitié-Salpêtrière, including the singer Josephine Baker in 1975, philosopher Michel Foucault in 1984, Diana, Princess of Wales in 1997,^[9] and French bicycle racer Laurent Fignon in 2010.

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